Over a century ago, Alois Alzheimer, a German psychiatrist, spotted strange plaques and tangles in the brain slides of a patient with dementia. Ever since, scientists have been trying to better understand the mechanisms behind what is now known as Alzheimer’s disease. Alzheimer’s disease (AD) is a brain disorder that[Read More…]
Tag: alzheimer’s
A new treatment for Alzheimer’s
Alzheimer’s disease currently affects around 44 million people worldwide. The disease destroys cells in the brain, inducing symptoms such as memory loss, mood swings, poor judgement, and a shortened attention span. The number of Canadians suffering from this debilitating illness is rising, but no cure or treatment currently exists to[Read More…]
Unlucky inheritance
There are many things in my life that I’ve accepted as inevitable: Breaking a bone, teenage heartbreak, and failing a final exam, for example, I have a strange sense that those events are predetermined. This may be symptomatic of a childhood spent in front of a television—each event in my[Read More…]
mRNA acts as marker in Alzheimer’s patients
Through mathematical modeling and collaboration with scientists at the University of California San Francisco (UCSF), McGill researchers, including Rached Alkallas, graduate student in the Department of Human Genetics and the primary author of the seminal study published in Nature Communications, have identified a protein that sharply decreases in patients with[Read More…]
Predicting Alzheimer’s with artificial intelligence
Researchers in the Douglas Mental Health University Institute’s Translational Neuroimaging Laboratory at McGill have created an artificial intelligence-based algorithm to recognize dementia before its onset—an elusive task, even for neurologists. The algorithm uses statistics to learn what the determining markers of the disease are—a process called machine learning, a branch[Read More…]
From skin cells to brain cells: McGill researchers generate a cell critical to Alzheimer’s research
Researchers at the Montreal Neurological Institute and Hospital (MNI) of McGill University have recently discovered a method for transforming patients’ skin cells into a type of brain cell critical for understanding and treating neurological disorders like Alzheimer’s disease. According to the McGill Newsroom, the artificial cells are “virtually indistinguishable from[Read More…]
MNI researchers create data model to isolate causes of Alzheimer’s disease
Alzheimer’s disease, first described by Alois Alzheimer in 1906, is a progressive brain disorder that causes debilitating cognitive impairments. Today, it is the most common cause of dementia, responsible for 60 to 70 per cent of 47.5 million cases worldwide. Due to its high prevalence, Alzheimer’s disease poses a significant[Read More…]
This Month in Student Research: Adam Marks
Dr. Claudio Cuello told Adam Marks that he could have a job if he found someone in the lab to take him on as an undergraduate researcher. Accepting the challenge, Marks approached a masters student to ask for a role. Two years later, the two of them are under review[Read More…]
ABCs of Science: Alzheimer’s
Alzheimer’s disease and related dementias affect an estimated 500,000 Canadians. A study by the Alzheimer Society of Canada (ASC) found the disease to be the second most feared by Canadians as they age, and with good reason—the disease leads to cognitive function resulting in impaired short-term memory, the inability to[Read More…]
